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Methadone is often a mu-agonist opioid by having an abuse liability just like morphine. Methadone, like morphine and other opioids utilized for analgesia, has the probable for getting abused and is particularly topic to legal diversion.Talka R, Salminen O, Tuominen RK: Methadone is really a non-aggressive antagonist for the alpha4beta2 and alpha3*